2010Achievements

2010 Original Papers
  1. Nagase Kenichi†, Kobayashi Jun, Kikuchi Akihiko, Akiyama Yoshikatsu, Kanazawa Hideko, Annaka Masahiko, Okano Teruo*, “Preparation of thermoresponsive anionic copolymer brush surfaces for separating basic biomolecules”, Biomacromolecules, 11(1):215-223(2010/01)
  2. Sato Tsuyoshi, Abe Takahiro, Chida Dai, Nakamoto Norimichi, Hori Naoko, Kokubu Shoichiro, Sakata Yasuaki, Tomaru Yasuhisa, Iwata Takanori, Usui Michihiko, Aiko Katsuya,Yoda Tetsuya, “Functional role of acetylcholine and the expression of cholinergic receptors and components in osteoblasts.”, FEBS letters, 584(4):817-824(2010/01)
  3. Mizutani Aya†, Nagase Kenichi, Kikuchi Akihiko, Kanazawa Hideko, Akiyama Yoshikatsu, Kobayashi Jun, Annaka Masahiro, Okano Teruo*, “Thermo-responsive polymer brush-grafted porous polystyrene beads for all-aqueous chromatography”, Journal of chromatography. A, 1217(4):522-529(2010/01)
  4. Ito Shinobu, Itoga Kazuyoshi, Yamato Masayuki, Akamatsu Hirohiko, Okano Teruo, “The co-application effects of fullerene and ascorbic and on UV-B irradiated mouse skin”, Toxicology, 267(1-3):27-38(2010/01)
  5. Kubo A†, Kim YH, Irion S, Kasuda S, Ogiwara K, Takeda T, Ohashi K, Iwano M, Dohi Y, Sato Y, Sanodgrass R, Keller G, “The homeobox gene HEX regulates hepatocyte differentiation from ES cell-derived endoderm.”, Hepatology International, 51(2):633-641(2010/02)
  6. Ohashi Kazuo†*, Koyama Fumikazu, Tatsumi Kohei, Shima Midori, Park Frank, Nakajima Yoshiyuki, Okano Teruo, “Functional life-long maintenance of engineered liver tissue in mice following transplantation under the kidney capsule.”, Journal of Tissue Engineering and Regenerative Medicine, 4(2):141-148(2010/02)
  7. Nagase Kenichi†, Kumazaki Mio, Kanazawa Hideko, Kobayashi Jun, Kikuchi Akihiko, Akiyama Yoshikatsu, Annaka Masahiko, Okano Teruo*, “Thermo-responsive polymer brush surfaces with hydrophobic groups for all-aqueous chromatography”, ACS Applied Materials & Interfaces, 2(4):1247-1253(2010/04)
  8. Nagai Toshihiro†, Sato Masato*, Kutsuna Toshiharu, Kokubo Mami, Ebihara Goro, Ohta Naoshi, Mochida Joji, “Intravenous administration of anti-vascular endothelial growth factor humanized monoclonal antibody bevacizumab improves articular cartilage repair.”, Arthritis research&therapy, 12(5):R178(2010/05)
  9. Asakawa N†,Shimizu T ,Tsuda Y, Sekiya S, Sasagawa T, Yamato M, Fukai F, Okano T*, “Pre-vascularization of in vitro three-dimensional tissues created by cell sheet engineering.”, Biomaterials, 31:3903-3909(2010/05)
  10. Sasagawa T†, Shimizu T, Sekiya S, Haraguchi Y, Yamato M, Sawa Y, Okano T*, “Design of prevascularized three-dimensional cell-dense tissues using a cell sheet stacking manipulation technology.”, Biomaterials, 31(7):1646-1654(2010/05)
  11. Hattori Yusuke†, Nagase Kenichi, Kobayashi Jun, Kikuchi Akihiko, Akiyama Yoshikatsu, Kanazawa Hideko, Annaka Masahiko, Okano Teruo*, “Hydration of poly(N-isopropylacrylamide) brushes on micro-silica beads measured by a fluorescent probe”, Chemical Physics Letters, 491(4-6):193-198(2010/05)
  12. Akimoto Jun†, Nakayama Masamichi, Sakai Kiyotaka, Okano Teruo*, “Thermally Controlled Intracellular Uptake System of Polymeric Micelles Possessing Poly(N-isopropylacrylamide)-Based Outer Coronas”, Molecular pharmaceutics, 7(4):926-935(2010/05)
  13. Kumashiro Yoshikazu†, Yamato Masayuki, Okano Teruo*, “Cell Attachment Detachment Control on Temperature-Responsive Thin Surfaces for Novel Tissue Engineering”, Annals of biomedical engineering, 38(6):1977-1988(2010/06)
  14. Ohashi Kazuo†*, Tatsumi Kohei, Utoh Rie, Takagi Soichi, Shima Midori, Okano Teruo, “Engineering liver tissues under the kidney capsule site provides therapeutic effects to hemophilia B mice.”, Cell transplantation, 19(6):807-13(2010/06)
  15. Haraguchi Yuji†, Shimizu Tatsuya, Yamato Masayuki, Okano Teruo*, “Electrical interaction between cardiomyocyte sheets separated by noncardiomyocyte sheets in heterogeneous tissues”, Journal of Tissue Engineering and Regenerative Medicine, 4(4):291-299(2010/06)
  16. Wang H†, Kawashima N*, Iwata T, Xu J, Takahashi S, Sugiyama T, Suda H., “Differentiation of odontoblasts is negatively regulated by MEPE via its C-terminal fragment.”, Biochemical and biophysical research communications, 398(3):406-12(2010/07)
  17. OKARA Hanayuki†, MATSUYAMA Akifumi, LEE Chun-Man, SAGA Ayami, KAKUTA-YAAMOTO Aya, NAGAO Annna, SOUGAWA Nagako, SEKIYA Naosumi, TAKEKITA Kazuhiro, SHUDO Yashuhiro, MIYAGAWA Shigeru, KOMODA Hiroshi, OKANO Teruo, SAWA Yoshiki, “Cardiomyoblast-like cells differentiated from human adipose tissue-derived mesenchymal stem cells improve left ventricular dysfunction and survival in a rat myocardial infarction model”, Tissue engineering, 16(3):417-425(2010/07)
  18. Aleksic Verica†, Aoki Akira*, Iwasaki Kengo, Takasaki Aristeo Atsushi, Wang Chen-Ying, Abiko Yoshimitsu, Ishikawa Isao, Izumi Yuichi, “Low-level Er:YAG laser irradiation enhances osteoblast proliferation through activation of MAPK/ERK.”, Lasers in medical science, 25(4):559-569(2010/07)
  19. Takahashi Hironobu†, Nakayama Masamichi, Yamato Masayuki, Okano Teruo, “Controlled Chain Length and Graft Density of Thermoresponsive Polymer Brushes for Optimizing Cell Sheet Harvest”, Biomacromolecules, 11(8):1991-1999(2010/08)
  20. Mizutani Aya†, Nagase Kenichi, Kikuchi Akihiko, Kanazawa Hideko, Akiyama Yoshikatsu, Kobayashi Jun, Annaka Masahiko, Teruo Okano*, “Effective separation of peptides using highly dense thermo-responsive polymer brush-grafted porous polystyrene beads”, Journal of Chromatography B, 878(24):2191-2198(2010/08)
  21. HAYASHIRyuhei†, YAMATOMasayuki, TKAYANAGIHiroshi, OIEYoshinori, KUBOTAAkira, HORIYuichi, OKANOTeruo, NISHIDAKohji*, “Validation system of tissue-engineered epithelial cell sheets for corneal regenerative medicine.”, Tissue engineering. Part C, Methods, 16(4):553-60(2010/08)
  22. MIYAGAWA Shigeru†, SAITO Atsuhiro, SAKAGUCHI Taichi, YOSHIKAWA Yasushi, YAMAUCHI Takashi, IMANISHI Yukikko, KAWAGUCHI Naomasu, TERAMOTO Noboru, MATSUURA Nariaki, IIDA Hidehiro, SHIMIZU Tatsuya, OKANO Teruo, SAWA Yoshiki*, “Impaired myocardium regeneration with skeletal cell sheets–a preclinical trial for tissue-engineered regeneration therapy.”, Transplantation, 90(4):364-72(2010/08)
  23. OIE Yoshinori†, HAYASHI Ryuhei, TAKAGI Ryo, YAMATO Masayuki, TAKAYANAGI Hiroshi, TANO Yasuo, NISHIDA Kohji*, “A novel method of culturing human oral mucosal epithelial cell sheet using post-mitotic human dermal fibroblast feeder cells and modified keratinocyte culture medium for ocular surface reconstruction.”, The British journal of ophthalmology, 94(9):1244-50(2010/09)
  24. Washio Kaoru†*, Iwata Takanori, Mizutani Manabu, Ando Tomohiro, Yamato Masayuki, okano Teruo*, Ishikawa Isao, “Assessment of cell sheets derived from human periodontal ligament cells:a pre-clinical study”, Cell and tissue research, 341(3):397-404(2010/09)
  25. Bel Alain†, Planat-Bernard Valerie , Saito Atsuhiro, Bonnevie Lionel , Bellamy Valerie , Sabbah Laurent , Bellabas Linda , Brinon Benjamin, Vanneaux Valerie , Pradeau Pascal , Peyrard Severine , Larghero Jerome , Pouly Julia , Binder Patrice , Garcia Sylvie , Shimizu Tatsuya, Sawa Yoshiki, Okano Teruo, Bruneval Patrick , Desnos Michel , Hagege Albert A. , Casteilla Louis , Puceat Michel , Menasche Philippe*, “Composite cell sheets: a further step toward safe and effective myocardial regeneration by cardiac progenitors derived from embryonic stem cells”, Circulation, 122(11(suppl1)):S118-S123(2010/09)
  26. Yoshida Toshiyuki, Miyoshi Jun, Takai Yoshimi, Thesleff Irma, “Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth.”, Developmental dynamics : an official publication of the American Association of Anatomists, 239(10):2558-69(2010/09)
  27. Mizutani Aya†, Nagase Kenichi, Kikuchi Akihiko, Kanazawa Hideko, Akiyama Yoshikatsu, Kobayashi Jun, Annaka Masahiro, Okano Teruo*, “Preparation of thermo-responsive polymer brushes on hydrophilic polymeric beads by surface-initiated atom transfer radical polymerization for a highly resolutive separation of peptides”, Journal of Chromatography A, 1217(38):5978-5985(2010/09)
  28. Tang Zhonglan†, Akiyama Yoshikatsu, Yamato Masayuki, Okano Teruo*, “Comb-type grafted poly(N-isopropylacrylamide) gel modified surfaces for rapid detachment of cell sheet”, Biomaterials, 31(29):7435-7443(2010/10)
  29. Itoga Kazuyoshi†, Kobayashi Jun, Yamato Masayuki, Okano Teruo*, “Development of microfabrication technology with maskless photolithography device using LCD projector”, Journal of Robotics and Mechatronics, 22(5):608-612(2010/10)
  30. Sasaki Ryo†*, Watanabe Yorikatsu, Yamato Masayuki, Aoki Shunsuke, Okano Teruo, Ando Tomohiro, “Surgical anatomy of the swine face”, Laboratory animals, 44(4):359-363(2010/10)
  31. Kazuhiro Fukumori†, Akiyama Yoshikatsu, Kumashiro Yoshikazu, Kobayashi Jun, Yamato Masayuki, Sakai Kiyotaka, Okano Teruo*, “Characterization of ultra-thin temperature-responsive polymer layer and its polymer thickness dependency on cell attachment/detachment properties”, Macromolecular bioscience, 10(10):1117-1129(2010/10)
  32. Idota Naokazu†, Nagase Kenichi, Tanaka Keiji, Okano Teruo, Annaka Masahiko*, “Stereoregulation of Thermoresponsive Polymer Brushes by Surface-Initiated Living Radical Polymerization and the Effect of Tacticity on Surface Wettability”, Langmuir, 26(23):17781-17784(2010/11)
  33. Duncan Thomas J†, Tanaka Yuji, Shi Dong, Kubota Akira, Quantock Andrew J, Nishida Kohji*, “Flow-manipulated, crosslinked collagen gels for use as corneal equivalents.”, Biomaterials, 31(34):8996-9005(2010/12)
  34. Elloumi-Hannachi Imen†, Maeda Masanori, Yamato Masayuki, Okano Teruo*, “Portable microcontact printing device for cell culture.”, Biomaterials, 31(34):8974-8979(2010/12)
  35. Sato T†*, Chida D, Iwata T, Usui M, Hatori K, Abe T, Takeda S, Yoda T., “Non-neuronal regulation and repertoire of cholinergic receptors in organs.”, Biomolecular Concepts, 1(5-6):357-366(2010/12)
  36. Iwata T†, Yamato M, Zhang Z, Mukobata S, Washio K, Ando T, Feijen J, Okano T*, Ishikawa I., “Validation of human periodontal ligament-derived cells as a reliable source for cytotherapeutic use.”, Journal of clinical periodontology, 37(12):1088-99(2010/12)
  37. Masakuni Tokunaga†, Mei-Lan Liu, Toshio Nagai, Koji Iwanaga, Katsuhisa Matsuura, Toshinao Takahashi, Masato Kanda, Naomichi Kondo, Pin Wang, Atsuhiko T. Naito, Issei Komuro*, “Implantation of cardiac progenitor cells using self-assembling peptide improves cardiac function after myocardial infarction.”, Journal of molecular and cellular cardiology, 49(6):972-983(2010/12)
  38. Sekiya S, Muraoka M, Sasagawa T, Shimizu T, Yamato M, Okano T., “Three-dimensional cell-dense constructs containing endothelial cell-networks are an 3 effective tool for in vivo and in vitro vascular biology research”, Microvascular research, 80(3):549-551(2010/12)
  39. HAYASHI Motohiro†*, CHERNOV Mikhail, TAMURA Noriko, NAGAI Mariko, YOMO Shoji, OCHIAI Taku, AMANO Kosaku, IZAWA Masahiro, HORI Tomotokatsu, MURAGAKI Yoshihiro, ISEKI Hiroshi, OKADA Yoshikazu, TAKAKURA Kintomo, “Gamma Knife robotic microradiosurgery of pituitary adenomas invading the cavernous sinus: treatment concept and results in 89 cases”, Journal of Neuro-Oncology, 98(2):185-194(2010/06)
2010　Review Papers
  1. Y. Kumashiro, M. Yamato and T. Okano, “Cell attachment-detachment control on temperature-responsive thin surfaces for novel tissue engineering”, Ann. Biomed. Eng., 38(6), 1977-88(2010 Jun).
  2. I. Elloumi-Hannachi, M. Yamato and T. Okano, “Cell sheet engineering: a unique nanotechnology for scaffold-free tissue reconstruction with clinical applications in regenerative medicine”, J. Intern. Med., 267(1), 54-70(2010 Jan).
  3. K. Itoga and T. Okano, “The high functionalization of temperature-responsive culture dishes for establishing advanced cell sheet engineering”, J. Mat. Chem., 20(40), 8768-8775(2010).

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