2012Achievements

Original Papers / Review Papers / Books / Newspaper /  Awards/

2012　原著論文
  1. 高久 裕子†, 村井 邦彦, 鵜養 拓, 伊藤 聡, 小久保 舞美, 小林 英司, 竹内 護, 持田 讓治, 佐藤 正人*, “整形外科領域における蛍光イメージング 軟骨再生　ラット膝関節内へ移植した細胞シートのBioluminescenceによる経時的評価”, 臨床整形外科, 47(1):27-31(2012/01)
  2. Takahashi Hironobu, Matsuzaka Naoki, Nakayama Masamichi, Kikuchi Akihiko, Yamato Masayuki, Okano Teruo, “Terminally functionalized thermoresponsive polymer brushes for simultaneously promoting cell adhesion and cell sheet harvest”, Biomacromolecules, 13(1):253(2012/01)
  3. Tatsumi Kohei†, Ohashi Kazuo*, Teramura Yuji, Utoh Rie, Kanegae Kazuko, Watanabe Natsumi, Mukobata Shigeki, Nakayama Masamichi, Iwata Hiroo, Okano Teruo, “The non-invasive cell surface modification of hepatocytes with PEG-lipid derivatives.”, Biomaterials, 33(3):821-8(2012/01)
  4. Terumasa Umemoto†, Masayuki Yamato1*, Jun Ishihara, Yoshiko Shiratsuchi,Mika Utsumi, Yohei Morita, Hiroko Tsukui, Masao Terasawa, Takehiko Shibata,Kohji Nishida, Yoshiro Kobayashi, Brian Petrich, Hiromitsu Nakauchi,Koji Eto*, Teruo Okano, “Integrin αvβ3 regulates thrombopoietin-mediated maintenance of hematopoietic stem cells”, Blood, 119(1):83-94(2012/01)
  5. Tatsumi Kohei†, Ohashi Kazuo*, Tateno Chise, Yoshizato Katsutoshi, Yoshioka Akira, Shima Midori, Okano Teruo*, “Human hepatocyte propagation system in the mouse livers: functional maintenance of the production of coagulation and anticoagulation factors”, Cell Transplantation, 21:437-445(2012/01)
  6. Kino-Oka Masahiro†, Ngo Trung Xuan, Nagamori Eiji, Takezawa Yasunori, Miyake Yasuki, Sawa Yoshiki, Saito Atsuhiro, Shimizu Tatsuya, Okano Teruo, Taya Masahito, “Evaluation of vertical fluidity in a multilayered sheet of skeletal myoblasts”, Journal of Bioscience and Bioengineering, 113(1):128-131(2012/01)
  7. Watanabe Yorikatsu†, Sasaki Ryo, Ando Tomohiro, Okano Teruo, Akizuki Tanetaka, “Multistage bone-charged distraction osteogenesis for aesthetic reconstruction of an extensive bone deficiency in the mandible.”, The Journal of craniofacial surgery, 23(1):175-177(2012/01)
  8. Sawa Yoshiki†, Miyagawa Shigeru , Sakaguchi Taichi , Fujita Tomoyuki, Matsuyama Akifumi , Saito Atsuhiro, Shimizu Tatsuya , Okano Teruo, “Tissue engineered myoblast sheets improved cardiac function sufficiently to discontinue LVAS in a patient with DCM: report of a case”, Surgery Today, 42(2):181-184(2012/01)
  9. Hayakawa Tomohiro†, Kunihiro Takeshi, Dowaki Suguru , Uno Hatsume, Matsui Eriko , Uchida Masashi , Kobayashi Seiji , Yasuda Akio , Shimizu Tatsuya, Okano Teruo*, “Noninvasive evaluation of contractile behavior of cardiomyocyte monolayers based on motion vector analysis”, Tissue Engineering Part C: Methods, 18(1):21-32(2012/01)
  10. Williams Corin†, Xie Angela W., Emani Sirisha, Yamato Masayuki, Okano Teruo, Emani Sitaram M., Wong Joyce Y.*, “A comparison of human smooth muscle and mesenchymal stem cells as potential cell sources for tissue-engineered vascular patches”, Tissue engineering, 18(9-10):986-998(2012/01)
  11. Suzuki Yoko†, Ohno Satoshi, okuyama Ryuji, Aruga Atsushi, Yamamoto Masakazu, MIura Shigeki, Yoshioka Hiroshi, Mori Yuichi, Suzuki Katsuhiko*, “Determinnation of Chronic Inflammatory States in Cancer Patients Using Assay of Reactive Oxygen Species Production by Neutrophils”, Anticancer research, 32:565-570(2012/02)
  12. Kim Kyungsook†, Ohashi Kazuo*, Utoh Rie, Kano Kyoko, Okano Teruo, “Preserved liver-specific functions of hepatocytes in 3D co-culture with endothelial cell sheets.”, Biomaterials, 33(5):1406-13(2012/02)
  13. Haraguchi Yuji†, Shimizu Tatsuya, Yamato Masayuki, Okano Teruo*, “Concise review: cell therapy and tissue engineering for cardiovascular disease.”, Stem cells translational medicine, 1(2):136-41(2012/02)
  14. Nagase Kenichi†, Kobayashi Jun, Kikuchi Akihiko, Akiyama Yoshikatsu, Kanazawa Hideko, Okano Teruo*, “High stability of thermoresponsive polymer-brush-grafted silica beads as chromatography matrices”, ACS Applied Materials & Interfaces, 4(4):1998-2008(2012/03)
  15. Ohashi Kazuo†*, Tatsumi Kohei, Chise Tateno, Miho Kataoka, Utoh Rie, Yoshizato Katsutoshi, Okano Teruo, “Liver tissue engineering utilizing hepatocytes propagated in mouse livers in vivo”, Cell transplantation, 21(2):429-436(2012/03)
  16. Takagi Soichi†, Ohno Maki†, Ohashi Kazuo*, Utoh Rie, Tatsumi Kohei, Okano Teruo, “Cell shape regulation based on hepatocyte sheet engineering technologies”, Cell transplantation, 21(1):411-420(2012/03)
  17. Shimizu Koichi†, Kotera Yoshihito, Aruga Atsushi, Takeshita Nobuhiro, Takasaki Ken, Yamamoto Masakazu, “Clinical utilization of postoperative dendritic cell vaccine plus activated T-cell transfer in patients with intrahepatic choloangiocarcinoma”, Journal of Hepato-Biliary-Pancreatic Sciences, 19(2):171-178(2012/03)
  18. Nishio Tadashi†, Kanazashi Ryosuke Eri, Nojima Akari, Kanazawa Hideko*, Okano Teruo, “Effect of polymer containing a naphthyl-alanine derivative on the separation selectivity for aromatic compounds in temperature-responsive chromatography.”, Journal of chromatography. A, 1228:148-154(2012/03)
  19. Nagase Kenichi†, Mukae Naoto, Kikuchi Akihiko, Okano Teruo*, “Thermally modulated retention of lymphoctytes on polymer-brush-grafted glass beads”, Macromolecular Bioscience, 12(3):333-340(2012/03)
  20. Tanaka Yuji†, Kubota Akira, Matsusaki Michiya, Duncan Thomas, Hatakeyama Yoshikiyo, Fukuyama Katsuya, Quantock Andrew J, Yamato Masayuki, Akashi Mitsuru, Nishida Kohji, “Anisotropic mechanical properties of collagen hydrogels induced by uniaxial-flow for ocular applications.”, Journal of Biomaterials Science, Polymer Edition, 22(11):1427-1442(2012/04)
  21. Yuji Haraguchi, Shimizu Tatsuya, Sasagawa Tadashi, Sekine Hidekazu, Sakaguchi Katsuhisa, Kikuchi Tetsutaro, Sekine Waki, Sekiya Sachiko, Yamato Masayuki, Umezu Mitsuo, Okano Teruo*, “Fabrication of functional three-dimensional tissues by stacking cell sheets in vitro”, Nature Protocols, 7(5):850-858(2012/04)
  22. 田中信行†*, 東森充, 金子真, “対象物変形に伴う流体力変動を考慮した非接触剛性センシング”, 計測自動制御学会論文集, 48(5):295-301(2012/05)
  23. Ebihara Goro†, Sato Masato*, Yamato Masayuki, Mitani Genya, Kutsuna Toshiharu, Nagai Toshihiro, Ito Satoshi, Ukai Taku, Kobayashi Miyuki, Kokubo Mami, Okano Teruo, Mochida Joji, “Cartilage repair in transplanted scaffold-free chondrocyte sheets using a minipig model.”, Biomaterials, 33(15):3846-51(2012/05)
  24. Tamura Atsushi†, Kobayashi Jun, Yamato Masayuki, Okano Teruo*, “Temperature-responsive poly(N-isopropylacrylamide)-grafted microcarriers for large-scale non-invasive harvest of anchorage-dependent cells”, Biomaterials, 33(15):3803-3812(2012/05)
  25. Tatsumi Kohei†, OHASHI KAZUO*, Mukobata Shigeki, Kubo Atsushi, Koyama Fumikazu, Nakajima Yohiyuki, Shima Midori, Okano Teruo*, “Hepatocyte is a sole cell type responsible for the production of coagulation factor IX in vivo”, Cell Medicine, 3:25-31(2012/05)
  26. OHASHI KAZUO†*, Matsubara Yoshinori, Tastumi Kohei, Kohori Ayako, UTOH Rie, Kakidachi Hiroshi, Horii Akihiro, Ttsutsumi Masahiro, Okano Teruo, “Cell therapy using adipose-derived stem cells for chronic liver injury in mice”, Cell Medicine, 3(1-3):113-119(2012/05)
  27. Kumashiro Yoshikazu†,Ikezoe Yasuhiro, Hayashi Tomohiro, Okabayashi Youichi, Yamato Masayuki, Okano Teruo, Hara Masahiko, “Temperature-modulated adsorption of poly(N-isopropylacrylamide)-grafted ferritin on solid substrate”, Colloids and Surfaces B: Biointerfaces, 95:57-64(2012/05)
  28. Satoshi Migita, Kazuyoshi Itoga, Jun Kobayashi, Teruo Okano, Akiyoshi Taniguchi, “Effect of Cell Density on Reproducibility in a Cell-Based Biosensor Using a Microwell Array”, Jounal of Biosensors & Bioelectronics, 3(3):1000118(2012/05)
  29. Matsuzaka Naoki, Takahashi Hironobu, Nakayama Masamichi, Kikuchi Akihiko, Okano Teruo*, “Effect of the hydrophobic basal layer of thermoresponsive block co-polymer brushes on thermally-induced cell sheet harvest”, Journal of Biomaterials Science, Polymer Edition, 23(10):1301-1314(2012/05)
  30. Itagaki K, Naito T, Iwakiri R, Haga M, Miura S, Saito Y, Owaki T, Kamiya S, Iyoda T, Yajima H, Iwashita S, Ejiri S, Fukai F., “Eukaryotic translation elongation factor 1A induces anoikis by triggering cell detachment.”, The Journal of biological chemistry, 287(19):16037-46(2012/05)
  31. Mikami Hiroshi†, Kuwahara Go, Nakamura Nobuyki, Yamato Masayuki, Tanaka Masatoshi, Kodama Shohta*, “Two-Layer tissue engineered urethra using oral epithelial and muscle derived cells”, The Journal of urology, 187(5):1882-1889(2012/05)
  32. Miki kenji†, Uenaka Hisazumi, Saito Atsuhiro, Miyagawa Shigeru , Sakaguchi Taichi , Higuchi Takahiro, Shimizu Tatsuya, Okano Teruo, Yamanaka Shinya, Sawa Yoshiki*, “Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats”, Stem Cells Translational Medicine, 1(5):430-437(2012/05)
  33. Ohno Satoshi†*, Okuyama Ryuji, Aruga Atsushi, Sugiyama Haruo, Yamamoto Masakazu, “Phase I Traial of Wilms’s Tumor 1(WT1) Peptide Vaccine with GM-CSF or CpG in Patients with Solid Malignancy”, Anticancer research, 32(6):2263(2012/06)
  34. Tamura Atsushi†, Nishi Masanori, Kobayashi Jun, Nagase Kenichi, Yajima Hirofumi, Yamato Masayuki, Okano Teruo*, “Simultaneous enhancement of cell proliferation and thermally induced harvest efficiency based on temperature-responsive cationic copolymer-grafted microcarriers”, Biomacromolecules, 13(6):1765-1773(2012/06)
  35. NAKAYAMA Masamichi†, Yamada Naoko, Kumashiro Yoshikazu, Kanazawa Hideko, Yamato Masayuki, Okano Teruo, “Thermoresponsive Poly(N-isopropylacrylamide)-Based Block Copolymer Coating for Optimizing Cell Sheet Fabrication”, Macromolecular bioscience, 12(6):751-760(2012/06)
  36. Masumoto Hidetoshi†, Matsuo Takehiko, Yamamizu Kohei, Uosaki Hideki, Narazaki Genta, Katayama Shiori, Marui Akira, Shimizu Tatsuya, Ikeda Tadashi, Okano Teruo, Sakata Ryuzo, Yamashita K Jun*, “Pluripotent Stem Cell-Engineered Cell Sheets Re-Assembled with Defined Cardiovascular Populations Ameliorate Reduction in Infarct Heart Function Through Cardiomyocyte-Mediated Neovascularization.”, Stem cells, 30(6):1196-1205(2012/06)
  37. Yuji Tanaka†, Yamato Ayako, Naoko Yaji, Yamato Masayuki*, “A simple stock of optical glasses for a catastrophic disaster: eyewear donations after the 2011 pacific coast Tohoku earthauake”, The Tohoku Journal of Experimental Medicine, 227(2):93-95(2012/06)
  38. Saito Shunsuke†, Miyagawa Shigeru, Sakaguchi Taichi, Imanishi Yukiko, Iseoka Hiroko, Nishi Hiroyuki , Yoshikawa Yasushi, Fukushima Satsuki, Saito Atsuhiro, Shimizu Tatsuya, Okano Teruo, Sawa Yoshiki*, “”Myoblast sheet can prevent the impairment of cardiac diastolic function and late remodeling after left ventricular restoration in ischemic cardiomyopathy””, Transplantation, 93(11):1108-1115(2012/06)
  39. Ito Satoshi†, Sato Masato*, Yamato Masayuki, Mitani Genya, Kutsuna Toshiharu, Nagai Toshihiro, Ukai Taku, Kobayashi Miyuki, Kokubo Mami, Okano Teruo, Mochida Joji, “Repair of articular cartilage defect with layered chondrocyte sheets and cultured synovial cells.”, Biomaterials, 33(21):5278-86(2012/07)
  40. Nagase Kenichi†, Kimura Ayaka, Shimizu Tatsuya, Matsuura Katsuhisa, Yamato Masayuki, Takeda Naoya, Okano Teruo*, “Dynamically cell separating thermo-functional biointerfaces with densely packed polymer brushes”, Journal of Materials Chemistry, 22(37):19514(2012/08)
  41. Matsuura Katsuhisa†, Wada Masanori, Shimizu Tatsuya, Haraguchi Yuji, Sato Fumiko, Sugiyama Kasumi, Konishi Kanako, Shiba Yuji, Ichikawa Hinako, Tachibana Aki, Ikeda Uichi, Yamato Masayuki, Nobuhisa Hagiwara, Okano Teruo*, “Creation of human cardiac cell sheets using pluripotent stem cells”, Biochemical and biophysical research communications, 425(2):321-327(2012/08)
  42. Kawamura Masashi†, Miyagawa Shigeru, Miki Kenji, Saito Atsuhiro, Fukushima Satsuki, Higuchi Takahiro, Kawamura Takuji, Kuratani Toru, Daimon Takashi, Shimizu Tatsuya, Okano Teruo, Sawa Yoshiki*, “Feasibility, safety, and therapeutic efficacy of human induced pluripotent stem cell-derived cardiomyocyte sheets in a porcine ischemic cardiomyopathy model”, Circulation, 126(11(suppl1)):S29-37(2012/09)
  43. Ohki Takeshi†, Yamato Masayuki, Ota Masaho, Takagi Ryo, Murakami Daisuke, Kondo Makoto, Sasaki Ryo, Namiki Hideo, Okano Teruo, Yamamoto Masakazu, “Prevention of Esophageal Stricture After Endoscopic Submucosal Dissection Using Tissue-Engineered Cell Sheets”, Gastroenterology, 143(3):582-588(2012/09)
  44. HAYASHI Ryuhei†, ISHIKAWA Yuki, ITO Miyuki, KAGEYAMA Tomofumi, TAKASHIBA Kuniko, FUJIOKA Tsuyoshi, TSUJIKAWA Motokazu, MIYOSHI Hiroyuki, YAMATO Masayuki, NAKAMURA Yukio, NISHIDA Kohji*, “Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium.”, PloS one, 7(9):e45435(2012/09)
  45. 熊代善一†, 岡野光夫, “細胞シート工学を用いた再生医療”, 日本香粧品学会誌, 36(3):189-193(2012/10)
  46. Tang Zhonglan†, Akiyama Yoshikatsu, Itoga Kazuyoshi, Kobayashi Jun, Yamato Masayuki, Okano Teruo*, “Shear stress-dependent cell detachment from temperature-responsive cell culture surfaces in a microfluidic device”, Biomaterials, 33(30):7405-7411(2012/10)
  47. Kanai Nobuo, Yamato Masayuki, Ohki Takeshi, Yamamoto Masakazu, Okano Teruo, “Fabricated autologous epidermal cellsheets for the prevention of esophageal stricture after circumferential ESD in a porcine model”, Gastrointestinal endoscopy, 7(4):873-881(2012/10)
  48. Sasaki Ryo†*, Yamato Masayuki, Takagi Ryo, Ohki Takashi, Matsumine Hajime, Okano Teruo, Ando Tomohiro, “Punch and spindle-shaped biopsies for collecting oral mucosal tissue for the fabrication of transplantable autologous epithelial cell sheets”, Journal of biomedical materials research. Part A, 100(10):2849-2854(2012/10)
  49. Tanaka Yuji†, Kubota Akira, Yokokura Shunji, Uematsu Masafumi, Shi Dong, Yamato Masayuki, Okano Teruo, Quantock Andrew J, Nishida Kohji*, “Optical mechanical refinement of human amniotic membrane by dehydration and cross-linking.”, Journal of tissue engineering and regenerative medicine, 6(9):731-7(2012/10)
  50. 酒井麻友子, 有賀淳, 小寺由人, 山本雅一, “HydroCellを用いた末梢血からの樹状細胞の培養”, 癌と化学療法, 39(12):1806-1808(2012/11)
  51. Tamura Atsushi†, Kobayashi Jun, Yamato Masayuki, Okano Teruo*, “Thermally responsive microcarriers with optimal poly(N-isopropylacrylamide) grafted density for facilitating cell adhesion/detachment in suspension culture”, Acta Biomaterialia, 8(11):3904-3913(2012/11)
  52. Yamada Masumi†, Utoh Rie†, Ohashi Kazuo, Tatsumi Kohei, Yamato Masayuki, Okano Teruo, Minoru Seki*, “Controlled formation of heterotypic hepatic micro-organoids in anisotropic hydrogel microfibers for long-term preservation of liver-specific functions”, Biomaterials, 33(33):8304-8315(2012/11)
  53. Idota Naokazu†, Kikuchi Akihiko, Kobayashi Jun, Sakai Kiyotaka, Okano Teruo*, “Modulation of graft architectures for enhancing hydrophobic interaction of biomolecules with thermoresponsive polymer-grafted surfaces”, Colloids and Surfaces B: Biointerfaces, 99:95-101(2012/11)
  54. Nakayama Masamichi, Kawahara Yayoi, Akimoto Jun, Kanazawa Hideko, Okano Teruo, “pH-induced phase transition control of thermoresponsive nano-micelles possessing outermost surface sulfonamide moieties”, Colloids and Surfaces B: Biointerfaces, 99:12-19(2012/11)
  55. Ayano Eri†, Karaki Miyuki, Ishihara Tsutomu, Kanazawa Hideko*, Okano Teruo, “Poly (N-isopropylacrylamide)-PLA and PLA blend nanoparticles for temperature-controllable drug release and intracellular uptake.”, Colloids and surfaces. B, Biointerfaces, 99:67-73(2012/11)
  56. Yoshida Toshiyuki†, Kumashiro Yoshikazu, Iwata Takanori, Ishihara Jun, Umemoto Terumasa, Kawashima Nobuyuki, Shiratsuchi Yoshiko, Sugiyama Toshihiro, Yamato Masayuki, Okano Teruo*, “Requirement of Integrin β3 for Iron Transportation during Enamel Formation”, Journal of Dental Research, 91(12):1154-9(2012/12)
  57. NAKAJIMA Ryota†, KOBAYASHI Toyoshige, MORIYA Noboru, MIZUTANI Manabu, KAN Kazutoshi, NOZAKI Takayuki, SAITO Kazuo, YAMATO Masayuki, OKANO Teruo, TAKEDA Shizu*, “A novel closed cell culture device for fabrication of corneal epithelial cell sheets.”, Journal of Tissue Engineering and Regenerative Medicine, 9(11):1259-67(2012/12)
  58. Matsuura Katsuhisa†, Shimizu Tatsuya, Yamato Masayuki, Hagiwara Nobuhisa, Okano Teruo*, “Fabrication of mouse embryonic stem cell-derived layered cardiac cell sheets using a bioreactor system”, PLoS ONE, 7(12):e52176(2012/12)
  59. TAKAGI Ryo†, YAMATO Masayuki*, KUSHIDA Ai, NISHIDA Kohji, OKANO Teruo, “Profiling of extracellular matrix and cadherin family gene expression in mouse feeder layer cells: type VI collagen is a candidate molecule inducing the colony formation of epithelial cells.”, Tissue engineering. Part A, 18(23-24):2539-48(2012/12)
  60. Kaoru Washio†, Hozue Kuroda, Takanori Iwata, Toshiyuki Yoshida, Masayuki Yamato, Teruo Okano, “Improved Enzymatic Treatment for Accurate Cell Counting from Extracellular Matrix-Rich Periodontal Ligament Cell Sheets”, Oral & Craniofacial Tissue Engineering, 2(3):185-189(2012)

Achievements

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